Searchable abstracts of presentations at key conferences in endocrinology

ea0031p74 | Clinical practice/governance and case reports | SFEBES2013

Spironolactone interference in the immunoassay of androstenedione in a patient with a cortisol-secreting adrenal adenoma

Broderick Deirdre , Crowley Rachel K , O'Shea Triona , Boran Gerard , Conlon Kevin , Maher Vincent , Gibney James , Sherlock Mark

A 48-year-old man was referred for investigation of uncontrolled hypertension on four agents (olmesartan, felodipine, hydrochlorothiazide and spironolactone) and a 3 cm right-sided adrenal adenoma (pre-contrast Hounsfield units 25). Endocrine investigation for the hypertension and adrenal mass included: androstenedione 19.9 nmol/l 2.8–10.5) (elevated on two occasions on a Siemens Coat-A-Count assay), DHEA 0.7 μmol/l (2.1–15.2), 1 mg overnight dexamethasone suppr...